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Biomarker Based Cancer Scenario: A preliminary study of the northeastern region in Bangladesh

MSony SA1, Islam MR1, Syeed Uddin HM2,Ishma T2 Fariha KA1, Hasnat MA1*,Syfuddin HM1*

1Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet-3114, Bangladesh. 2Department of Microbiology, Stamford University Bangladesh, 51, Siddeswari Road, Dhaka-1217, Bangladesh.

ABSTRACT: Cancer, one of the major cause of mortality worldwide, has become a big threat to developing countries like Bangladesh because of its increased prevalence rate every year. Based on diagnosis and treatment modalities, this article inspects into various types of cancer incidences in a small sample from Sylhet, a city of Bangladesh, prior to any large-scale investigation representing the whole metropolis. Within the samples studied, the rate and frequency of cancer, incidences of each type of cancer in different genders and correlation of sex, age and malignancy are observed. Next, on the basis of reference values, the affected ones are separated from the entire samples. The highest number of the affected samples resides within an age range of 35-70 years where each type of biomarker indicates some specific type of cancer in a short age interval. Breast and ovarian cancers occur in the female at early mid-age and postmenopausal time whereas in men prostate cancer is mostly frequent after middle age e.g. from 71 to 80. Overall, since most of the samples are female, consequently cancer incidence rate is also noticeably higher in them compared to the males.

KEYWORDS: Cancer biomarker, Age, Sex, Prevalence.



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